SCCS Final Opinions on Hydroxyapatite (Nano) and UV Filters

Posted Date: 12-August-2025

EU Corrigendum on Fragrance Allergens

 

The following summarizes four final opinions from the Scientific Committee on Consumer Safety (SCCS) published in late June and early July 2025.

Hydroxyapatite (Nano):

The SCCS concluded that a specific type of rod-shaped hydroxyapatite (nano) is safe for use in toothpaste (up to 29.5%) and mouthwash (up to 10%). This is based on findings that it does not pose a mutagenic or cytotoxic risk and that any ingested particles dissolve rapidly in the stomach. The opinion does not apply to needle-shaped particles.

UV Filter Ethylhexyl Methoxycinnamate (EHMC):

The SCCS deemed EHMC safe for use as a UV filter up to a maximum concentration of 10% in various sunscreen and cosmetic products, including those for children, despite it being identified as an “endocrine active substance.”

UV Filters Benzophenone-2 (BP-2) and Benzophenone-5 (BP-5):

The SCCS could not conclude on the safety of BP-2 due to concerns about genotoxicity and its endocrine-active properties. However, it found BP-5 to be safe when used as a UV filter up to a maximum concentration of 5%, based on data from a similar substance, BP-4.

 

 

Impurity in UV Filter Diethylamino Hydroxybenzoyl Hexyl Benzoate (DHHB):

The SCCS established a maximum safe level of 0.026% (260 ppm) for the impurity DnHexP in the UV filter DHHB. It also recommended a target of 1 ppm as the maximal level for this unavoidable trace impurity.