Research Institute for Fragrance Materials (RIFM) Concentration Survey 049

Posted Date: 23-September-2025

Research Institute for Fragrance Materials

 

The Research Institute for Fragrance Materials (RIFM) has launched its 49th concentration survey to obtain exposure data on 146 fragrance materials and carryovers.  The survey is intended to be completed by fragrance compounders for marketed fragrance mixtures, rather than finished cosmetic products.  Exposure data are essential for the completion of a safety assessment for all human health endpoints; if there are no exposure data, then RIFM will not conduct a safety assessment.  The Creme RIFM Aggregate Exposure Model is a probabilistic aggregate exposure model to calculate total systemic exposure, with distributions used to model various parameters; more information on this can be found in this publication.

This Excel sheet provides the list of materials for this survey. The Excel file contains two worksheets. The first worksheet contains the 147 fragrance materials included in this survey. Please note that for natural complex substances (NCSs), the RIFM identifier is more important than the CAS Number because it incorporates the ISO Standard (ISO 9235) nomenclature.  Please note that as of this survey, additional product types are included; and companies will need to add the total number of formulas sold for each product type.  The concentration data will remain confidential.