European Union Ban on TPO – Nailing Down the Risk of Nail Polishes and Gels

Posted Date: 23-September-2025

European Union Ban on TPO - Nailing Down the Risk of Nail Polishes and Gels

 

The article by Joe Shawrtz highlights the recent EU ban on trimethylbenzoyl diphenylphosphine oxide (TPO), a chemical used in gel nail polish. The ban stems from animal studies that showed reproductive toxicity when TPO was ingested. The central argument is the difference between the EU’s “hazard” approach and the U.S. and Canadian “risk” approach to chemical regulation. The EU bans a substance based on its potential for harm, even if the actual risk of human exposure is low. In contrast, other regulators consider the level of human exposure to determine the actual risk. Joe Shawrtz concludes that while the ban will force European manufacturers to reformulate their products, it addresses a potential hazard rather than an actual risk, as humans do not ingest nail gel.